# Intrathecal Dexmedetomidine-Fentanyl Combination Versus Fentanyl Alone as Adjuvant to Bupivacaine in Spinal Anesthesia for Above Knee Amputation in Sarcomas of Lower Extremity

> **NCT07276867** · NA · RECRUITING · sponsor: **National Cancer Institute, Egypt** · enrollment: 58 (estimated)

## Conditions studied

- Intrathecal
- Dexmedetomidine
- Fentanyl
- Bupivacaine
- Spinal Anesthesia
- Above Knee Amputation
- Sarcomas
- Lower Extremity

## Interventions

- **DRUG:** Fentanyl + Dexmedetomidine
- **DRUG:** Fentanyl

## Key facts

- **NCT ID:** NCT07276867
- **Lead sponsor:** National Cancer Institute, Egypt
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2025-10-20
- **Primary completion:** 2026-04-01
- **Final completion:** 2026-04-01
- **Target enrollment:** 58 (ESTIMATED)
- **Last updated:** 2025-12-11


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07276867

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07276867, "Intrathecal Dexmedetomidine-Fentanyl Combination Versus Fentanyl Alone as Adjuvant to Bupivacaine in Spinal Anesthesia for Above Knee Amputation in Sarcomas of Lower Extremity". Retrieved via AI Analytics 2026-06-23 from https://api.ai-analytics.org/clinical/NCT07276867. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*
