# Combined Brain Stimulation and Methylphenidate Treatment for Apathy in Dementia

> **NCT07279740** · PHASE2 · RECRUITING · sponsor: **Sunnybrook Health Sciences Centre** · enrollment: 12 (estimated)

## Conditions studied

- Alzheimer s Disease
- Alzheimer Dementia (AD)
- Alzheimer Dementia
- Alzheimer Disease
- Apathy
- Apathy in Dementia

## Interventions

- **DEVICE:** intermittent theta burst stimulation (iTBS)
- **DRUG:** Methylphenidate (MPH)

## Key facts

- **NCT ID:** NCT07279740
- **Lead sponsor:** Sunnybrook Health Sciences Centre
- **Sponsor class:** OTHER
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2026-01
- **Primary completion:** 2027-10-01
- **Final completion:** 2027-10-01
- **Target enrollment:** 12 (ESTIMATED)
- **Last updated:** 2025-12-12

## Collaborators

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- [object Object]
- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07279740

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07279740, "Combined Brain Stimulation and Methylphenidate Treatment for Apathy in Dementia". Retrieved via AI Analytics 2026-06-08 from https://api.ai-analytics.org/clinical/NCT07279740. Licensed CC0.

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