# Step-down Therapy After Long-term Osteoporosis Treatment

> **NCT07281586** · PHASE4 · RECRUITING · sponsor: **National Taiwan University Hospital** · enrollment: 44 (estimated)

## Conditions studied

- Osteoporosis

## Interventions

- **DRUG:** zoledronate
- **DRUG:** zoledronate
- **DRUG:** Denosumab De-escalation

## Key facts

- **NCT ID:** NCT07281586
- **Lead sponsor:** National Taiwan University Hospital
- **Sponsor class:** OTHER
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2026-01-01
- **Primary completion:** 2028-12-31
- **Final completion:** 2028-12-31
- **Target enrollment:** 44 (ESTIMATED)
- **Last updated:** 2025-12-15

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07281586

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07281586, "Step-down Therapy After Long-term Osteoporosis Treatment". Retrieved via AI Analytics 2026-06-16 from https://api.ai-analytics.org/clinical/NCT07281586. Licensed CC0.

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