# Capecitabine/Oxaliplatin Chemotherapy and Cemiplimab With or Without Fianlimab or REGN7075 in Locally Advanced Rectal Cancer

> **NCT07281768** · PHASE2 · NOT_YET_RECRUITING · sponsor: **Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins** · enrollment: 66 (estimated)

## Conditions studied

- Colorectal Cancer

## Interventions

- **DRUG:** Oxaliplatin
- **DRUG:** Capecitabine
- **DRUG:** Cemiplimab
- **DRUG:** Fianlimab
- **DRUG:** REGN7075

## Key facts

- **NCT ID:** NCT07281768
- **Lead sponsor:** Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
- **Sponsor class:** OTHER
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** NOT_YET_RECRUITING
- **Start date:** 2026-07
- **Primary completion:** 2030-07
- **Final completion:** 2030-07
- **Target enrollment:** 66 (ESTIMATED)
- **Last updated:** 2026-05-06

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07281768

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07281768, "Capecitabine/Oxaliplatin Chemotherapy and Cemiplimab With or Without Fianlimab or REGN7075 in Locally Advanced Rectal Cancer". Retrieved via AI Analytics 2026-06-08 from https://api.ai-analytics.org/clinical/NCT07281768. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*