# Biologicals in Management of Intra-Bony Defects

> **NCT07292870** · NA · RECRUITING · sponsor: **Universitaire Ziekenhuizen KU Leuven** · enrollment: 30 (estimated)

## Conditions studied

- Intra-bony Pockets
- Periodontitis

## Interventions

- **BIOLOGICAL:** Minimally invasive surgical treatment of the intra-bony defects
- **BIOLOGICAL:** Use of the xenograft Bio-Oss® Collagen during the surgery
- **BIOLOGICAL:** Use of enamel matrix derivative (Emdogain®)
- **BIOLOGICAL:** Use of hyaluronic acid (REGENFAST®)
- **BIOLOGICAL:** use of the blood derivative L-PRF (leukocyte and platelet rich fibrin)

## Key facts

- **NCT ID:** NCT07292870
- **Lead sponsor:** Universitaire Ziekenhuizen KU Leuven
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2025-08-08
- **Primary completion:** 2027-12-31
- **Final completion:** 2027-12-31
- **Target enrollment:** 30 (ESTIMATED)
- **Last updated:** 2026-03-17


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07292870

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07292870, "Biologicals in Management of Intra-Bony Defects". Retrieved via AI Analytics 2026-05-27 from https://api.ai-analytics.org/clinical/NCT07292870. Licensed CC0.

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