# Impact of Semaglutide Withdrawal on Cardiometabolic Profile and Physiology of Energy Balance: Recovery Effects After Semaglutide Termination

> **NCT07294950** · PHASE3 · RECRUITING · sponsor: **Mount Sinai Hospital, Canada** · enrollment: 98 (estimated)

## Conditions studied

- Obesity (Disorder)
- Weight Change
- Blood Pressure Monitoring
- Appetite Regulation

## Interventions

- **DRUG:** Gradual dose reduction of semaglutide
- **DRUG:** Abrupt cessation of semaglutide

## Key facts

- **NCT ID:** NCT07294950
- **Lead sponsor:** Mount Sinai Hospital, Canada
- **Sponsor class:** OTHER
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2026-02-01
- **Primary completion:** 2028-09
- **Final completion:** 2029-05
- **Target enrollment:** 98 (ESTIMATED)
- **Last updated:** 2026-02-11

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07294950

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07294950, "Impact of Semaglutide Withdrawal on Cardiometabolic Profile and Physiology of Energy Balance: Recovery Effects After Semaglutide Termination". Retrieved via AI Analytics 2026-06-08 from https://api.ai-analytics.org/clinical/NCT07294950. Licensed CC0.

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