# Study of an RSV-hMPV-PIV3 Trivalent Vaccine Candidate VXB-251 in Older Adults

> **NCT07295028** · PHASE1 · ACTIVE_NOT_RECRUITING · sponsor: **Vicebio Australia Proprietary Limited** · enrollment: 240 (actual)

## Conditions studied

- Lower Respiratory Tract Disease
- Healthy Participants

## Interventions

- **BIOLOGICAL:** trivalent (RSV/hMPV/PIV3) vaccine candidate
- **BIOLOGICAL:** trivalent (RSV/hMPV/PIV3) vaccine candidate
- **BIOLOGICAL:** trivalent (RSV/hMPV/PIV3) vaccine candidate
- **BIOLOGICAL:** bivalent (RSV/hMPV) unlicensed comparator
- **BIOLOGICAL:** monovalent (RSV) unlicensed comparator
- **BIOLOGICAL:** Biological/Vaccine: monovalent (hMPV) unlicensed comparator
- **BIOLOGICAL:** monovalent (PIV3) unlicensed comparator
- **OTHER:** Placebo

## Key facts

- **NCT ID:** NCT07295028
- **Lead sponsor:** Vicebio Australia Proprietary Limited
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** ACTIVE_NOT_RECRUITING
- **Start date:** 2025-11-17
- **Primary completion:** 2026-04-21
- **Final completion:** 2027-04-24
- **Target enrollment:** 240 (ACTUAL)
- **Last updated:** 2026-04-27


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07295028

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07295028, "Study of an RSV-hMPV-PIV3 Trivalent Vaccine Candidate VXB-251 in Older Adults". Retrieved via AI Analytics 2026-05-27 from https://api.ai-analytics.org/clinical/NCT07295028. Licensed CC0.

---

*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*