# Effect of Antifungals on the Intestinal Microbiome - a Randomized, Controlled, Proof-of-concept Trial

> **NCT07295314** · EARLY_PHASE1 · NOT_YET_RECRUITING · sponsor: **Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)** · enrollment: 50 (estimated)

## Conditions studied

- Gut Microbiome
- Healthy Adult Male
- Antifungal Therapy

## Interventions

- **DRUG:** Fluconazole 200mg tab

## Key facts

- **NCT ID:** NCT07295314
- **Lead sponsor:** Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
- **Sponsor class:** OTHER
- **Phase:** EARLY_PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** NOT_YET_RECRUITING
- **Start date:** 2026-01
- **Primary completion:** 2027-10
- **Final completion:** 2027-12
- **Target enrollment:** 50 (ESTIMATED)
- **Last updated:** 2025-12-19

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07295314

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07295314, "Effect of Antifungals on the Intestinal Microbiome - a Randomized, Controlled, Proof-of-concept Trial". Retrieved via AI Analytics 2026-06-25 from https://api.ai-analytics.org/clinical/NCT07295314. Licensed CC0.

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