# Low-intensity Hippocampal Transcranial Ultrasound Stimulation for Managing Cognitive and Sleep Dysfunction in Preclinical Alzheimer's Disease

> **NCT07298876** · NA · ENROLLING_BY_INVITATION · sponsor: **Chinese University of Hong Kong** · enrollment: 20 (estimated)

## Conditions studied

- Sleep Disturbances
- Aging
- Cognitive Impairment, Mild

## Interventions

- **DEVICE:** Low-intensity transcranial ultrasound stimulation
- **DEVICE:** Sham low-intensity transcranial ultrasound stimulation

## Key facts

- **NCT ID:** NCT07298876
- **Lead sponsor:** Chinese University of Hong Kong
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** ENROLLING_BY_INVITATION
- **Start date:** 2026-04-01
- **Primary completion:** 2027-03-31
- **Final completion:** 2027-05-16
- **Target enrollment:** 20 (ESTIMATED)
- **Last updated:** 2025-12-23

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07298876

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07298876, "Low-intensity Hippocampal Transcranial Ultrasound Stimulation for Managing Cognitive and Sleep Dysfunction in Preclinical Alzheimer's Disease". Retrieved via AI Analytics 2026-06-24 from https://api.ai-analytics.org/clinical/NCT07298876. Licensed CC0.

---

*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*