# NEXUS Study: A Study to Test Single and Multiple Doses of MER511 Given to Adults With Graves' Disease

> **NCT07305818** · PHASE1 · RECRUITING · sponsor: **Merida Biosciences** · enrollment: 100 (estimated)

## Conditions studied

- Graves Disease

## Interventions

- **BIOLOGICAL:** MER511 (IV)
- **BIOLOGICAL:** Placebo comparator (IV)
- **BIOLOGICAL:** MER511 (SC)
- **BIOLOGICAL:** Placebo comparator (SC)
- **BIOLOGICAL:** MER511 (SC) for MAD
- **BIOLOGICAL:** Placebo comparator (SC) for MAD

## Key facts

- **NCT ID:** NCT07305818
- **Lead sponsor:** Merida Biosciences
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2025-12-19
- **Primary completion:** 2028-07-24
- **Final completion:** 2028-07-24
- **Target enrollment:** 100 (ESTIMATED)
- **Last updated:** 2026-04-24


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07305818

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07305818, "NEXUS Study: A Study to Test Single and Multiple Doses of MER511 Given to Adults With Graves' Disease". Retrieved via AI Analytics 2026-05-29 from https://api.ai-analytics.org/clinical/NCT07305818. Licensed CC0.

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