# A Phase I Clinical Trial of a mRNA Vaccine for Recurrent or Progressive High-grade Glioma

> **NCT07306299** · PHASE1 · RECRUITING · sponsor: **Second Affiliated Hospital, School of Medicine, Zhejiang University** · enrollment: 10 (estimated)

## Conditions studied

- Glioma, High Grade

## Interventions

- **BIOLOGICAL:** Glioma-related multi-target mRNA vaccines

## Key facts

- **NCT ID:** NCT07306299
- **Lead sponsor:** Second Affiliated Hospital, School of Medicine, Zhejiang University
- **Sponsor class:** OTHER
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2025-12-01
- **Primary completion:** 2028-01-01
- **Final completion:** 2031-01-01
- **Target enrollment:** 10 (ESTIMATED)
- **Last updated:** 2025-12-29


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07306299

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07306299, "A Phase I Clinical Trial of a mRNA Vaccine for Recurrent or Progressive High-grade Glioma". Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/clinical/NCT07306299. Licensed CC0.

---

*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*