# Comparison of Self-Locking Versus Traditional Sutures in Double-Layer Laparoscopic Vaginal Vault Closure After Hysterectomy (BI-SURE Trial)

> **NCT07313839** · NA · RECRUITING · sponsor: **Azienda Ospedaliero-Universitaria di Parma** · enrollment: 310 (estimated)

## Conditions studied

- Gynecologic Cancers
- Vaginal Cuff Dehiscence
- Postoperative Complications

## Interventions

- **PROCEDURE:** Double-Layer Vaginal Vault Closure with Self-Locking Suture
- **PROCEDURE:** Double-Layer Vaginal Vault Closure with Polyglactin 910

## Key facts

- **NCT ID:** NCT07313839
- **Lead sponsor:** Azienda Ospedaliero-Universitaria di Parma
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2025-10-07
- **Primary completion:** 2027-01
- **Final completion:** 2027-01
- **Target enrollment:** 310 (ESTIMATED)
- **Last updated:** 2026-01-02


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07313839

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07313839, "Comparison of Self-Locking Versus Traditional Sutures in Double-Layer Laparoscopic Vaginal Vault Closure After Hysterectomy (BI-SURE Trial)". Retrieved via AI Analytics 2026-09-17 from https://api.ai-analytics.org/clinical/NCT07313839. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*