# The Effects of Preoperative Intranasal Administration of Dexmedetomidine and Esketamine on Negative Postoperative Behavioral Changes in Children With Autism Spectrum Disorder

> **NCT07324057** · NA · RECRUITING · sponsor: **Sun Fei** · enrollment: 234 (estimated)

## Conditions studied

- Autism Spectrum Disorder

## Interventions

- **DRUG:** Intranasal dexmedetomidine
- **DRUG:** Intranasal Esketamine
- **DRUG:** saline control

## Key facts

- **NCT ID:** NCT07324057
- **Lead sponsor:** Sun Fei
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2026-04-01
- **Primary completion:** 2027-02-01
- **Final completion:** 2027-11-30
- **Target enrollment:** 234 (ESTIMATED)
- **Last updated:** 2026-04-15

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07324057

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07324057, "The Effects of Preoperative Intranasal Administration of Dexmedetomidine and Esketamine on Negative Postoperative Behavioral Changes in Children With Autism Spectrum Disorder". Retrieved via AI Analytics 2026-05-26 from https://api.ai-analytics.org/clinical/NCT07324057. Licensed CC0.

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