# Study of Low-Intensity Focused Ultrasound in Combination With Immunotherapy in Newly Diagnosed Unmethylated Glioblastoma

> **NCT07343986** · PHASE1 · RECRUITING · sponsor: **University of Virginia** · enrollment: 12 (estimated)

## Conditions studied

- Glioblastoma (GBM)

## Interventions

- **DRUG:** anti-EGFR bispecific-armed T cells
- **DEVICE:** Low-Intensity Focused Ultrasound

## Key facts

- **NCT ID:** NCT07343986
- **Lead sponsor:** University of Virginia
- **Sponsor class:** OTHER
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2026-03-23
- **Primary completion:** 2027-12
- **Final completion:** 2028-12
- **Target enrollment:** 12 (ESTIMATED)
- **Last updated:** 2026-05-06

## Collaborators

- [object Object]
- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07343986

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07343986, "Study of Low-Intensity Focused Ultrasound in Combination With Immunotherapy in Newly Diagnosed Unmethylated Glioblastoma". Retrieved via AI Analytics 2026-06-02 from https://api.ai-analytics.org/clinical/NCT07343986. Licensed CC0.

---

*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*