# Flex Appeal: Evaluating the Efficacy of Anesthetic Techniques for Manipulation of Knees Under Anesthesia

> **NCT07348614** · PHASE4 · NOT_YET_RECRUITING · sponsor: **Duke University** · enrollment: 128 (estimated)

## Conditions studied

- Knee Stiffness After Total Knee Arthroplasty

## Interventions

- **PROCEDURE:** Spinal Anesthesia
- **PROCEDURE:** General Anesthesia
- **DRUG:** Propofol
- **DRUG:** Chloroprocaine

## Key facts

- **NCT ID:** NCT07348614
- **Lead sponsor:** Duke University
- **Sponsor class:** OTHER
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** NOT_YET_RECRUITING
- **Start date:** 2026-03
- **Primary completion:** 2027-08
- **Final completion:** 2027-09
- **Target enrollment:** 128 (ESTIMATED)
- **Last updated:** 2026-01-16


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07348614

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07348614, "Flex Appeal: Evaluating the Efficacy of Anesthetic Techniques for Manipulation of Knees Under Anesthesia". Retrieved via AI Analytics 2026-06-25 from https://api.ai-analytics.org/clinical/NCT07348614. Licensed CC0.

---

*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*