# Exploratory Study on mRNA Therapeutic Drug Targeting CD19 for the Treatment of Hematologic Malignancies

> **NCT07349849** · EARLY_PHASE1 · RECRUITING · sponsor: **Xinqiao Hospital of Chongqing** · enrollment: 47 (estimated)

## Conditions studied

- B-cell Malignancies

## Interventions

- **DRUG:** in vivo CAR-T drug based on LNP-mRNA

## Key facts

- **NCT ID:** NCT07349849
- **Lead sponsor:** Xinqiao Hospital of Chongqing
- **Sponsor class:** OTHER
- **Phase:** EARLY_PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2025-12-20
- **Primary completion:** 2028-01-01
- **Final completion:** 2028-12-31
- **Target enrollment:** 47 (ESTIMATED)
- **Last updated:** 2026-01-20


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07349849

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07349849, "Exploratory Study on mRNA Therapeutic Drug Targeting CD19 for the Treatment of Hematologic Malignancies". Retrieved via AI Analytics 2026-07-11 from https://api.ai-analytics.org/clinical/NCT07349849. Licensed CC0.

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