# Cyclophosphamide and Etoposide as a Metronomic Therapy in Advanced Head and Neck Squamous Cell Cancer

> **NCT07361133** · PHASE2 · NOT_YET_RECRUITING · sponsor: **National Cancer Institute, Egypt** · enrollment: 120 (estimated)

## Conditions studied

- Squamous Cell Carcinoma
- Advanced Head and Neck Cancer

## Interventions

- **DRUG:** Cyclophosphamide and Etoposide in combination
- **DRUG:** Methotrexate

## Key facts

- **NCT ID:** NCT07361133
- **Lead sponsor:** National Cancer Institute, Egypt
- **Sponsor class:** OTHER
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** NOT_YET_RECRUITING
- **Start date:** 2026-04
- **Primary completion:** 2026-08
- **Final completion:** 2026-09
- **Target enrollment:** 120 (ESTIMATED)
- **Last updated:** 2026-04-16


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07361133

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07361133, "Cyclophosphamide and Etoposide as a Metronomic Therapy in Advanced Head and Neck Squamous Cell Cancer". Retrieved via AI Analytics 2026-05-29 from https://api.ai-analytics.org/clinical/NCT07361133. Licensed CC0.

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