# Esketamine With or Without Integration Therapy for Treatment-Resistant Depression

> **NCT07369102** · PHASE4 · RECRUITING · sponsor: **University of Puerto Rico** · enrollment: 20 (estimated)

## Conditions studied

- Treatment-resistant Depression (TRD)

## Interventions

- **DRUG:** Esketamine hydrochloride (intranasal)
- **BEHAVIORAL:** Integration Therapy

## Key facts

- **NCT ID:** NCT07369102
- **Lead sponsor:** University of Puerto Rico
- **Sponsor class:** OTHER
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2026-02-01
- **Primary completion:** 2026-12-01
- **Final completion:** 2026-12-01
- **Target enrollment:** 20 (ESTIMATED)
- **Last updated:** 2026-01-27


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07369102

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07369102, "Esketamine With or Without Integration Therapy for Treatment-Resistant Depression". Retrieved via AI Analytics 2026-06-01 from https://api.ai-analytics.org/clinical/NCT07369102. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*