# Investigation of the Effects of Oxidized Antigens on the T-Cell Response and the Epigenetic Reprogramming of Neutrophils in Lung Diseases - OXIGENE -

> **NCT07386912** · — · NOT_YET_RECRUITING · sponsor: **Research Center Borstel** · enrollment: 100 (estimated)

## Conditions studied

- Asthma
- COPD
- Bacterial Pneumonia
- Viral Pneumonia
- Tuberculosis

## Interventions

- **OTHER:** Characterization of the neutrophil granulocyte epigenome
- **OTHER:** Characterization of the T-cell immune response to to various oxidatively modified mycobacterial antigens

## Key facts

- **NCT ID:** NCT07386912
- **Lead sponsor:** Research Center Borstel
- **Sponsor class:** OTHER
- **Phase:** —
- **Study type:** OBSERVATIONAL
- **Status:** NOT_YET_RECRUITING
- **Start date:** 2026-02-01
- **Primary completion:** 2028-12
- **Final completion:** 2030-12
- **Target enrollment:** 100 (ESTIMATED)
- **Last updated:** 2026-02-04


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07386912

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07386912, "Investigation of the Effects of Oxidized Antigens on the T-Cell Response and the Epigenetic Reprogramming of Neutrophils in Lung Diseases - OXIGENE -". Retrieved via AI Analytics 2026-07-19 from https://api.ai-analytics.org/clinical/NCT07386912. Licensed CC0.

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