# A Study of Safety and Drug Levels of ePGT121v1-LS, PGDM1400LS, and VRC07-523LS in Adult Participants Without HIV-1

> **NCT07390955** · PHASE1 · RECRUITING · sponsor: **National Institute of Allergy and Infectious Diseases (NIAID)** · enrollment: 83 (estimated)

## Conditions studied

- HIV

## Interventions

- **BIOLOGICAL:** ePGT121v1-LS (IV)
- **BIOLOGICAL:** PGDM1400LS (IV)
- **BIOLOGICAL:** VRC07-523LS (IV)
- **BIOLOGICAL:** ePGT121v1-LS (SC)
- **BIOLOGICAL:** PGDM1400LS (SC)
- **BIOLOGICAL:** VRC07-523LS (SC)

## Key facts

- **NCT ID:** NCT07390955
- **Lead sponsor:** National Institute of Allergy and Infectious Diseases (NIAID)
- **Sponsor class:** NIH
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2026-03-19
- **Primary completion:** 2027-08-30
- **Final completion:** 2027-08-30
- **Target enrollment:** 83 (ESTIMATED)
- **Last updated:** 2026-04-22

## Collaborators

- [object Object]
- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07390955

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07390955, "A Study of Safety and Drug Levels of ePGT121v1-LS, PGDM1400LS, and VRC07-523LS in Adult Participants Without HIV-1". Retrieved via AI Analytics 2026-05-28 from https://api.ai-analytics.org/clinical/NCT07390955. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*
