# Daily Tadalafil 5 mg Combined With On-Demand Sildenafil 100 mg for Treatment of Erectile Dysfunction in PDE-5I Non Responder Patients

> **NCT07391579** · PHASE4 · RECRUITING · sponsor: **Mansoura University** · enrollment: 500 (estimated)

## Conditions studied

- Erectile Dysfunctions

## Interventions

- **DRUG:** Tadalafil 5 mg & Sildenafil 100mg
- **DRUG:** Sildenafil 100mg & placebo

## Key facts

- **NCT ID:** NCT07391579
- **Lead sponsor:** Mansoura University
- **Sponsor class:** OTHER
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2025-12-01
- **Primary completion:** 2026-12
- **Final completion:** 2027-06
- **Target enrollment:** 500 (ESTIMATED)
- **Last updated:** 2026-02-06

## Collaborators

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## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07391579

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07391579, "Daily Tadalafil 5 mg Combined With On-Demand Sildenafil 100 mg for Treatment of Erectile Dysfunction in PDE-5I Non Responder Patients". Retrieved via AI Analytics 2026-06-25 from https://api.ai-analytics.org/clinical/NCT07391579. Licensed CC0.

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