# Efficacy of a Polyhexanide Biguanide-Based Gel in the Prevention of Biofilm Formation in Pressure Ulcers

> **NCT07391748** · EARLY_PHASE1 · NOT_YET_RECRUITING · sponsor: **Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana** · enrollment: 140 (estimated)

## Conditions studied

- Pressure Ulcers
- Pressure Ulcers Stage III
- Pressure Ulcer Prevention
- Pressure Ulcer ( Stage 2-3)
- Biofilm Formation
- Biofilm
- Biofilm Removal

## Interventions

- **COMBINATION_PRODUCT:** To determine the efficacy of a gel containing polyhexanide and biguanide, alone or in combination with alginate with or without silver, in preventing biofilm in PU, in terms of healing at 4 weeks

## Key facts

- **NCT ID:** NCT07391748
- **Lead sponsor:** Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana
- **Sponsor class:** OTHER
- **Phase:** EARLY_PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** NOT_YET_RECRUITING
- **Start date:** 2026-01-30
- **Primary completion:** 2026-04-30
- **Final completion:** 2026-09-30
- **Target enrollment:** 140 (ESTIMATED)
- **Last updated:** 2026-02-10


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07391748

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07391748, "Efficacy of a Polyhexanide Biguanide-Based Gel in the Prevention of Biofilm Formation in Pressure Ulcers". Retrieved via AI Analytics 2026-07-10 from https://api.ai-analytics.org/clinical/NCT07391748. Licensed CC0.

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