# Combined Use of a Respiratory Multiplex PCR and Algorithm-based Therapy to Improve Early Optimization of Antibiotic Therapy in Critically Ill Patients With Ventilator-associated Pneumonia

> **NCT07403474** · PHASE4 · NOT_YET_RECRUITING · sponsor: **Centre Hospitalier Universitaire de Nīmes** · enrollment: 124 (estimated)

## Conditions studied

- Ventilator Associated Pneumonia ( VAP)

## Interventions

- **PROCEDURE:** strategy combining respiratory mPCR and algorithm-based therapy developed using local epidemiology

## Key facts

- **NCT ID:** NCT07403474
- **Lead sponsor:** Centre Hospitalier Universitaire de Nīmes
- **Sponsor class:** OTHER
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** NOT_YET_RECRUITING
- **Start date:** 2026-06-01
- **Primary completion:** 2026-07-31
- **Final completion:** 2026-07-31
- **Target enrollment:** 124 (ESTIMATED)
- **Last updated:** 2026-02-12


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07403474

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07403474, "Combined Use of a Respiratory Multiplex PCR and Algorithm-based Therapy to Improve Early Optimization of Antibiotic Therapy in Critically Ill Patients With Ventilator-associated Pneumonia". Retrieved via AI Analytics 2026-06-02 from https://api.ai-analytics.org/clinical/NCT07403474. Licensed CC0.

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