# Neoadjuvant Immunotherapy ± Radiotherapy in MSI-H/dMMR Locally Advanced Colorectal Cancer

> **NCT07403877** · PHASE2 · NOT_YET_RECRUITING · sponsor: **Fudan University** · enrollment: 114 (estimated)

## Conditions studied

- Colorectal Cancer (MSI-H)

## Interventions

- **DRUG:** Nivolumab
- **DRUG:** Ipilimumab (1mg/kg)
- **RADIATION:** PULSAR
- **PROCEDURE:** Radical surgery
- **OTHER:** Watch & wait

## Key facts

- **NCT ID:** NCT07403877
- **Lead sponsor:** Fudan University
- **Sponsor class:** OTHER
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** NOT_YET_RECRUITING
- **Start date:** 2026-02-01
- **Primary completion:** 2031-12-31
- **Final completion:** 2034-12-31
- **Target enrollment:** 114 (ESTIMATED)
- **Last updated:** 2026-02-11


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07403877

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07403877, "Neoadjuvant Immunotherapy ± Radiotherapy in MSI-H/dMMR Locally Advanced Colorectal Cancer". Retrieved via AI Analytics 2026-06-08 from https://api.ai-analytics.org/clinical/NCT07403877. Licensed CC0.

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