# A Study of ORX489 in Healthy Adult Participants, Aged 18 to 60 Years

> **NCT07413666** · PHASE1 · RECRUITING · sponsor: **Centessa Pharmaceuticals (UK) Limited** · enrollment: 212 (estimated)

## Conditions studied

- Healthy Adult Male and Female Volunteers

## Interventions

- **DRUG:** ORX489 Tablets
- **OTHER:** Placebo Tablets

## Key facts

- **NCT ID:** NCT07413666
- **Lead sponsor:** Centessa Pharmaceuticals (UK) Limited
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2026-02-25
- **Primary completion:** 2027-06-30
- **Final completion:** 2027-06-30
- **Target enrollment:** 212 (ESTIMATED)
- **Last updated:** 2026-02-25


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07413666

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07413666, "A Study of ORX489 in Healthy Adult Participants, Aged 18 to 60 Years". Retrieved via AI Analytics 2026-05-25 from https://api.ai-analytics.org/clinical/NCT07413666. Licensed CC0.

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