# Natural History of Dysregulation and Aging of the Immune System in People With Trisomy 21 With and Without Thymectomy

> **NCT07416201** · — · RECRUITING · sponsor: **National Institute of Allergy and Infectious Diseases (NIAID)** · enrollment: 700 (estimated)

## Conditions studied

- Down Syndrome

## Interventions

_None listed._

## Key facts

- **NCT ID:** NCT07416201
- **Lead sponsor:** National Institute of Allergy and Infectious Diseases (NIAID)
- **Sponsor class:** NIH
- **Phase:** —
- **Study type:** OBSERVATIONAL
- **Status:** RECRUITING
- **Start date:** 2026-05-21
- **Primary completion:** 2040-05-01
- **Final completion:** 2040-11-01
- **Target enrollment:** 700 (ESTIMATED)
- **Last updated:** 2026-05-18


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07416201

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07416201, "Natural History of Dysregulation and Aging of the Immune System in People With Trisomy 21 With and Without Thymectomy". Retrieved via AI Analytics 2026-05-25 from https://api.ai-analytics.org/clinical/NCT07416201. Licensed CC0.

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