# Phase I/II Clinical Trial of Diphtheria-Tetanus-Pertussis (Reduced Dose) Vaccine

> **NCT07418372** · PHASE1,PHASE2 · NOT_YET_RECRUITING · sponsor: **Institute of Medical Biology, Chinese Academy of Medical Sciences** · enrollment: 660 (estimated)

## Conditions studied

- Tetanus, Diphtheria and Acellular Pertussis Vaccination
- Tetanus
- Diphtheria
- Pertussis
- Pertussis Vaccines

## Interventions

- **BIOLOGICAL:** low-dose Tetanus, Diphtheria and Acellular Component Pertussis Vaccine Adsorbed (Reduced Antigens Content)
- **BIOLOGICAL:** high-dose Tetanus, Diphtheria and Acellular Component Pertussis Vaccine Adsorbed (Reduced Antigens Content)
- **BIOLOGICAL:** Tetanus, Diphtheria and Acellular Pertussis Vaccine
- **BIOLOGICAL:** 23-valent polysaccharide pneumococcal vaccine

## Key facts

- **NCT ID:** NCT07418372
- **Lead sponsor:** Institute of Medical Biology, Chinese Academy of Medical Sciences
- **Sponsor class:** OTHER
- **Phase:** PHASE1,PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** NOT_YET_RECRUITING
- **Start date:** 2026-03-12
- **Primary completion:** 2026-08-31
- **Final completion:** 2027-07-31
- **Target enrollment:** 660 (ESTIMATED)
- **Last updated:** 2026-02-18


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07418372

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07418372, "Phase I/II Clinical Trial of Diphtheria-Tetanus-Pertussis (Reduced Dose) Vaccine". Retrieved via AI Analytics 2026-07-19 from https://api.ai-analytics.org/clinical/NCT07418372. Licensed CC0.

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