# 5-Fluorouracil Response and Optimization STudy (The FROST Trial)

> **NCT07419464** · PHASE2 · RECRUITING · sponsor: **Washington University School of Medicine** · enrollment: 46 (estimated)

## Conditions studied

- Squamous Cell Carcinoma of Head and Neck
- Metastatic Squamous Cell Carcinoma
- Recurrent Squamous Cell Carcinoma of the Head and Neck

## Interventions

- **DRUG:** 5-Fluorouracil

## Key facts

- **NCT ID:** NCT07419464
- **Lead sponsor:** Washington University School of Medicine
- **Sponsor class:** OTHER
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2026-04-21
- **Primary completion:** 2028-07-31
- **Final completion:** 2031-07-31
- **Target enrollment:** 46 (ESTIMATED)
- **Last updated:** 2026-04-27

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07419464

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07419464, "5-Fluorouracil Response and Optimization STudy (The FROST Trial)". Retrieved via AI Analytics 2026-06-09 from https://api.ai-analytics.org/clinical/NCT07419464. Licensed CC0.

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