# Ketone Monitoring Approaches for Diabetic Ketoacidosis Risk Mitigation in People With T1D on Adjunctive SGLT-2 Inhibitors

> **NCT07421518** · PHASE2 · NOT_YET_RECRUITING · sponsor: **AdventHealth Translational Research Institute** · enrollment: 75 (estimated)

## Conditions studied

- Type 1 Diabetes
- Type 2 Diabetes

## Interventions

- **DRUG:** SGLT-2 inhibitor (Sotagliflozin)
- **OTHER:** Insulin withdrawal test (IWT)

## Key facts

- **NCT ID:** NCT07421518
- **Lead sponsor:** AdventHealth Translational Research Institute
- **Sponsor class:** OTHER
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** NOT_YET_RECRUITING
- **Start date:** 2026-06
- **Primary completion:** 2030-04
- **Final completion:** 2030-04
- **Target enrollment:** 75 (ESTIMATED)
- **Last updated:** 2026-02-19


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07421518

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07421518, "Ketone Monitoring Approaches for Diabetic Ketoacidosis Risk Mitigation in People With T1D on Adjunctive SGLT-2 Inhibitors". Retrieved via AI Analytics 2026-07-04 from https://api.ai-analytics.org/clinical/NCT07421518. Licensed CC0.

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