# Cryoneurolysis Prior to Total Knee Arthroplasty (CRYO-TKA Trial)

> **NCT07425457** · NA · RECRUITING · sponsor: **Attikon Hospital** · enrollment: 100 (estimated)

## Conditions studied

- Arthroplasty
- Replacement Material
- Knee Arthritis Osteoarthritis
- Knee Arthroplasty, Total
- Genicular Nerves
- Chronic Pain

## Interventions

- **PROCEDURE:** CT-guided Cryoneurolysis of the Genicular Nerves

## Key facts

- **NCT ID:** NCT07425457
- **Lead sponsor:** Attikon Hospital
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2026-01-02
- **Primary completion:** 2027-12-31
- **Final completion:** 2028-03-31
- **Target enrollment:** 100 (ESTIMATED)
- **Last updated:** 2026-02-20


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07425457

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07425457, "Cryoneurolysis Prior to Total Knee Arthroplasty (CRYO-TKA Trial)". Retrieved via AI Analytics 2026-05-26 from https://api.ai-analytics.org/clinical/NCT07425457. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*
