# Comparative Study of Leflunomide Plus Methotrexate Versus Methotrexate Monotherapy in Refractory Polyarticular Juvenile Idiopathic Arthritis Patients

> **NCT07428551** · PHASE4 · COMPLETED · sponsor: **Bangladesh Medical University** · enrollment: 50 (actual)

## Conditions studied

- Juvenile Idiopathic Arthritis
- Polyarticular Juvenile Idiopathic Arthritis
- Refractory Polyarticular Juvenile Idiopathic Arthritis

## Interventions

- **DRUG:** Leflunomide plus Methotrexate
- **DRUG:** Methotrexate Monotherapy

## Key facts

- **NCT ID:** NCT07428551
- **Lead sponsor:** Bangladesh Medical University
- **Sponsor class:** OTHER
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2024-03-01
- **Primary completion:** 2025-12-31
- **Final completion:** 2026-01-28
- **Target enrollment:** 50 (ACTUAL)
- **Last updated:** 2026-02-23


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07428551

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07428551, "Comparative Study of Leflunomide Plus Methotrexate Versus Methotrexate Monotherapy in Refractory Polyarticular Juvenile Idiopathic Arthritis Patients". Retrieved via AI Analytics 2026-05-26 from https://api.ai-analytics.org/clinical/NCT07428551. Licensed CC0.

---

*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*