# Post-Operative Pain Relief: Zynrelef or Periarticular Injections in RATKA

> **NCT07430085** · PHASE4 · NOT_YET_RECRUITING · sponsor: **Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)** · enrollment: 150 (estimated)

## Conditions studied

- Periarticular Block
- Osteoarthritis (OA)
- Osteoarthritis (OA) of the Knee
- Pain After Surgery
- Knee Arthroplasty, Total

## Interventions

- **COMBINATION_PRODUCT:** bupivacaine-meloxicam (extended release)
- **DRUG:** Bupivacaine
- **DRUG:** Ketorolac
- **DRUG:** Lidocaine (drug)

## Key facts

- **NCT ID:** NCT07430085
- **Lead sponsor:** Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)
- **Sponsor class:** OTHER
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** NOT_YET_RECRUITING
- **Start date:** 2026-01-31
- **Primary completion:** 2028-01-31
- **Final completion:** 2028-02-28
- **Target enrollment:** 150 (ESTIMATED)
- **Last updated:** 2026-02-27


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07430085

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07430085, "Post-Operative Pain Relief: Zynrelef or Periarticular Injections in RATKA". Retrieved via AI Analytics 2026-06-03 from https://api.ai-analytics.org/clinical/NCT07430085. Licensed CC0.

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