# Trial to Evaluate Nonavalent HPV Vaccine as a Secondary Prevention in Patients Treated for Human Papilloma Virus Related High-grade Squamous Intraepithelial Lesions

> **NCT07431502** · PHASE3 · NOT_YET_RECRUITING · sponsor: **Gustave Roussy, Cancer Campus, Grand Paris** · enrollment: 984 (estimated)

## Conditions studied

- Patients With Primary HPV High-grade Squamous Intra-epithelial Lesions (HSIL) at Vulvar Site
- Patients With Primary HPV High-grade Squamous Intra-epithelial Lesions (HSIL) at Vaginal Site
- Patients With Primary HPV High-grade Squamous Intra-epithelial Lesions (HSIL) at Penile Site
- Patients With Primary HPV High-grade Squamous Intra-epithelial Lesions (HSIL) at Cervical Site
- Patients With Primary HPV High-grade Squamous Intra-epithelial Lesions (HSIL) at Anal Site

## Interventions

- **BIOLOGICAL:** HPV vaccine
- **BIOLOGICAL:** Placebo vaccine

## Key facts

- **NCT ID:** NCT07431502
- **Lead sponsor:** Gustave Roussy, Cancer Campus, Grand Paris
- **Sponsor class:** OTHER
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** NOT_YET_RECRUITING
- **Start date:** 2026-05
- **Primary completion:** 2030-11
- **Final completion:** 2030-11
- **Target enrollment:** 984 (ESTIMATED)
- **Last updated:** 2026-02-27


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07431502

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07431502, "Trial to Evaluate Nonavalent HPV Vaccine as a Secondary Prevention in Patients Treated for Human Papilloma Virus Related High-grade Squamous Intraepithelial Lesions". Retrieved via AI Analytics 2026-05-29 from https://api.ai-analytics.org/clinical/NCT07431502. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*