# Intrapleural Alteplase-Tyloxapol vs Intrapleural Alteplase-DNase in Pleural Infection

> **NCT07432373** · — · NOT_YET_RECRUITING · sponsor: **National University of Malaysia** · enrollment: 80 (estimated)

## Conditions studied

- Pleural Infection

## Interventions

- **DRUG:** Intrapleural t-PA/Dnase arm
- **DRUG:** t-PA (Alteplase) 5-10mg and Tyloxapol 200mg

## Key facts

- **NCT ID:** NCT07432373
- **Lead sponsor:** National University of Malaysia
- **Sponsor class:** OTHER
- **Phase:** —
- **Study type:** OBSERVATIONAL
- **Status:** NOT_YET_RECRUITING
- **Start date:** 2026-04-01
- **Primary completion:** 2028-06-01
- **Final completion:** 2028-07-01
- **Target enrollment:** 80 (ESTIMATED)
- **Last updated:** 2026-03-02

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07432373

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07432373, "Intrapleural Alteplase-Tyloxapol vs Intrapleural Alteplase-DNase in Pleural Infection". Retrieved via AI Analytics 2026-09-07 from https://api.ai-analytics.org/clinical/NCT07432373. Licensed CC0.

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