# Effect of Perioperative Lidocaine or High-Dose Dexamethasone on Immune Response in Colon Cancer Surgery (PILDI Study)

> **NCT07432399** · PHASE2 · RECRUITING · sponsor: **Institute of Oncology Ljubljana** · enrollment: 100 (estimated)

## Conditions studied

- Colon Cancer
- Colorectal Cancer
- Perioperative Immune Response

## Interventions

- **DRUG:** Lidocaine
- **DRUG:** Dexamethasone
- **DRUG:** Placebo

## Key facts

- **NCT ID:** NCT07432399
- **Lead sponsor:** Institute of Oncology Ljubljana
- **Sponsor class:** OTHER
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2025-09-01
- **Primary completion:** 2027-05-01
- **Final completion:** 2027-05-01
- **Target enrollment:** 100 (ESTIMATED)
- **Last updated:** 2026-03-06


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07432399

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07432399, "Effect of Perioperative Lidocaine or High-Dose Dexamethasone on Immune Response in Colon Cancer Surgery (PILDI Study)". Retrieved via AI Analytics 2026-07-05 from https://api.ai-analytics.org/clinical/NCT07432399. Licensed CC0.

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