# Prospective, Randomized, Multicenter Clinical Trial of Bisphosphonates Combined With Vancomycin for the Treatment of Cierny-Mader Type I and III Osteomyelitis

> **NCT07435051** · PHASE3 · NOT_YET_RECRUITING · sponsor: **Second Affiliated Hospital, School of Medicine, Zhejiang University** · enrollment: 280 (estimated)

## Conditions studied

- Osteomyelitis (Refractory)

## Interventions

- **DRUG:** Bisphosphonates Combined with Vancomycin
- **DRUG:** Vancomycin

## Key facts

- **NCT ID:** NCT07435051
- **Lead sponsor:** Second Affiliated Hospital, School of Medicine, Zhejiang University
- **Sponsor class:** OTHER
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** NOT_YET_RECRUITING
- **Start date:** 2026-05-01
- **Primary completion:** 2029-12-31
- **Final completion:** 2030-12-31
- **Target enrollment:** 280 (ESTIMATED)
- **Last updated:** 2026-02-27


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07435051

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07435051, "Prospective, Randomized, Multicenter Clinical Trial of Bisphosphonates Combined With Vancomycin for the Treatment of Cierny-Mader Type I and III Osteomyelitis". Retrieved via AI Analytics 2026-07-06 from https://api.ai-analytics.org/clinical/NCT07435051. Licensed CC0.

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