# NEUROCUPLE™ as an Opioid Alternative Following Total Knee Arthroplasty

> **NCT07439666** · NA · NOT_YET_RECRUITING · sponsor: **Jacques E. Chelly** · enrollment: 274 (estimated)

## Conditions studied

- Total Knee Arthroplasty Postoperative Pain
- Opioid Reduction After TKA

## Interventions

- **DEVICE:** NEUROCUPLE™ Patch
- **DEVICE:** Sham patch
- **OTHER:** Enhanced Recovery After Surgery (ERAS) Standard of Care

## Key facts

- **NCT ID:** NCT07439666
- **Lead sponsor:** Jacques E. Chelly
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** NOT_YET_RECRUITING
- **Start date:** 2026-05
- **Primary completion:** 2026-11
- **Final completion:** 2027-11
- **Target enrollment:** 274 (ESTIMATED)
- **Last updated:** 2026-04-08

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07439666

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07439666, "NEUROCUPLE™ as an Opioid Alternative Following Total Knee Arthroplasty". Retrieved via AI Analytics 2026-05-25 from https://api.ai-analytics.org/clinical/NCT07439666. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*