# The Impact of Saline Temperature and Local Anesthetic Adjuvants on Postoperative Shoulder Pain and Inflammatory Marker Levels Following Laparoscopic Cholecystectomy

> **NCT07450781** · NA · ENROLLING_BY_INVITATION · sponsor: **Alexandria University** · enrollment: 216 (estimated)

## Conditions studied

- Shoulder Pain , Laparoscopic Cholecystectomy

## Interventions

- **OTHER:** Room-temperature saline (25-30 ml/kg ) irrigation without local anesthetic.
- **OTHER:** Room-temperature saline (25-30 ml/kg l) with local anesthetic ( 0.25% bupivacaine according to body weight).
- **OTHER:** Warm saline (37°C, 25-30 ml/kg ) irrigation without local anesthetic.
- **OTHER:** Warm saline (37°C, 25-30 ml/kg) with local anesthetic (0.25% bupivacaine).
- **OTHER:** No saline irrigation.
- **OTHER:** No saline irrigation but with local anesthetic (local anesthetic instillation at trocar sites).

## Key facts

- **NCT ID:** NCT07450781
- **Lead sponsor:** Alexandria University
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** ENROLLING_BY_INVITATION
- **Start date:** 2026-02-01
- **Primary completion:** 2026-08-01
- **Final completion:** 2027-08-01
- **Target enrollment:** 216 (ESTIMATED)
- **Last updated:** 2026-03-17


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07450781

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07450781, "The Impact of Saline Temperature and Local Anesthetic Adjuvants on Postoperative Shoulder Pain and Inflammatory Marker Levels Following Laparoscopic Cholecystectomy". Retrieved via AI Analytics 2026-06-02 from https://api.ai-analytics.org/clinical/NCT07450781. Licensed CC0.

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