# ART Trial: Transcatheter J-VALVE Versus Surgery for Aortic Regurgitation Therapy

> **NCT07453407** · NA · RECRUITING · sponsor: **Second Affiliated Hospital, School of Medicine, Zhejiang University** · enrollment: 1250 (estimated)

## Conditions studied

- Aortic Regurgitation
- Aortic Valve Insufficiency
- Aortic Insufficiency

## Interventions

- **DEVICE:** J-VALVE Transfemoral Aortic Valve system
- **DEVICE:** Commercially available surgical biological aortic valve replacement device

## Key facts

- **NCT ID:** NCT07453407
- **Lead sponsor:** Second Affiliated Hospital, School of Medicine, Zhejiang University
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2026-03-05
- **Primary completion:** 2029-03
- **Final completion:** 2038-03
- **Target enrollment:** 1250 (ESTIMATED)
- **Last updated:** 2026-03-10


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07453407

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07453407, "ART Trial: Transcatheter J-VALVE Versus Surgery for Aortic Regurgitation Therapy". Retrieved via AI Analytics 2026-07-08 from https://api.ai-analytics.org/clinical/NCT07453407. Licensed CC0.

---

*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*