# Effect Of Different Sodium Hypochlorite Concentrations On Intracanal Substance P, CGRP And Opiorphin Levels And Postoperative Pain During Root Canal Retreatment

> **NCT07453576** · NA · RECRUITING · sponsor: **KEZBAN MELTEM ÇOLAK** · enrollment: 60 (estimated)

## Conditions studied

- Persistent Apical Periodontitis

## Interventions

- **DRUG:** Sodium Hypochlorite 1% Irrigation
- **DRUG:** Sodium Hypochlorite 2.5% Irrigation
- **DRUG:** Sodium Hypochlorite 5% Irrigation

## Key facts

- **NCT ID:** NCT07453576
- **Lead sponsor:** KEZBAN MELTEM ÇOLAK
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2025-10-01
- **Primary completion:** 2026-12-01
- **Final completion:** 2027-02-01
- **Target enrollment:** 60 (ESTIMATED)
- **Last updated:** 2026-03-06


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07453576

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07453576, "Effect Of Different Sodium Hypochlorite Concentrations On Intracanal Substance P, CGRP And Opiorphin Levels And Postoperative Pain During Root Canal Retreatment". Retrieved via AI Analytics 2026-07-05 from https://api.ai-analytics.org/clinical/NCT07453576. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*