# Effect of Low-Dose Versus High-Dose Alpha-Lipoic Acid on Oxidative Stress, Inflammation, and Clinical Outcomes in Acute Exacerbations of Chronic Obstructive Pulmonary Disease

> **NCT07456176** · PHASE3 · NOT_YET_RECRUITING · sponsor: **Ain Shams University** · enrollment: 75 (estimated)

## Conditions studied

- Acute Exacerbation Chronic Obstructive Pulmonary Disease

## Interventions

- **DRUG:** Alpha Lipoic Acid 600 MG Oral Tablets
- **DRUG:** Alpha Lipoic Acid
- **DRUG:** Placebo

## Key facts

- **NCT ID:** NCT07456176
- **Lead sponsor:** Ain Shams University
- **Sponsor class:** OTHER
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** NOT_YET_RECRUITING
- **Start date:** 2026-02-28
- **Primary completion:** 2026-05-28
- **Final completion:** 2026-06-01
- **Target enrollment:** 75 (ESTIMATED)
- **Last updated:** 2026-03-30


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07456176

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07456176, "Effect of Low-Dose Versus High-Dose Alpha-Lipoic Acid on Oxidative Stress, Inflammation, and Clinical Outcomes in Acute Exacerbations of Chronic Obstructive Pulmonary Disease". Retrieved via AI Analytics 2026-05-26 from https://api.ai-analytics.org/clinical/NCT07456176. Licensed CC0.

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