# Mandibular Advancement to Reduce Ventricular Load and Improve Quality-of-life in Heart Failure

> **NCT07460505** · NA · NOT_YET_RECRUITING · sponsor: **National University Hospital, Singapore** · enrollment: 328 (estimated)

## Conditions studied

- Heart Failure
- OSA - Obstructive Sleep Apnea

## Interventions

- **DEVICE:** Mandibular advancement device
- **DEVICE:** Mandibular advancement device (Sham)

## Key facts

- **NCT ID:** NCT07460505
- **Lead sponsor:** National University Hospital, Singapore
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** NOT_YET_RECRUITING
- **Start date:** 2026-05-01
- **Primary completion:** 2031-04-01
- **Final completion:** 2031-04-01
- **Target enrollment:** 328 (ESTIMATED)
- **Last updated:** 2026-03-10

## Collaborators

- [object Object]
- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07460505

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07460505, "Mandibular Advancement to Reduce Ventricular Load and Improve Quality-of-life in Heart Failure". Retrieved via AI Analytics 2026-07-16 from https://api.ai-analytics.org/clinical/NCT07460505. Licensed CC0.

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