# Intranasal Dexmedetomidine-esketamine Administration and Postoperative Pain in Pediatric Patients

> **NCT07479602** · PHASE4 · RECRUITING · sponsor: **Peking University First Hospital** · enrollment: 160 (estimated)

## Conditions studied

- Adenotonsillectomy
- Children
- Intranasal Administration
- Dexmedetomidine
- Esketamine
- Postoperative Pain

## Interventions

- **DRUG:** Intranasal dexmedetomidine-esketamine
- **DRUG:** Intranasal placebo (normal saline)

## Key facts

- **NCT ID:** NCT07479602
- **Lead sponsor:** Peking University First Hospital
- **Sponsor class:** OTHER
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2026-04-07
- **Primary completion:** 2027-02
- **Final completion:** 2027-02
- **Target enrollment:** 160 (ESTIMATED)
- **Last updated:** 2026-04-09


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07479602

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07479602, "Intranasal Dexmedetomidine-esketamine Administration and Postoperative Pain in Pediatric Patients". Retrieved via AI Analytics 2026-05-27 from https://api.ai-analytics.org/clinical/NCT07479602. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*