# Pilot and Feasibility Study of Intra-articular Anti-CD14 for the Treatment of Knee Osteoarthritis

> **NCT07481474** · PHASE1 · NOT_YET_RECRUITING · sponsor: **VA Office of Research and Development** · enrollment: 30 (estimated)

## Conditions studied

- Knee Osteoarthritis (Knee OA)

## Interventions

- **BIOLOGICAL:** Atibuclimab (intra-articular)
- **OTHER:** saline placebo

## Key facts

- **NCT ID:** NCT07481474
- **Lead sponsor:** VA Office of Research and Development
- **Sponsor class:** FED
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** NOT_YET_RECRUITING
- **Start date:** 2026-06-01
- **Primary completion:** 2027-06-01
- **Final completion:** 2028-01-01
- **Target enrollment:** 30 (ESTIMATED)
- **Last updated:** 2026-03-18


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07481474

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07481474, "Pilot and Feasibility Study of Intra-articular Anti-CD14 for the Treatment of Knee Osteoarthritis". Retrieved via AI Analytics 2026-08-03 from https://api.ai-analytics.org/clinical/NCT07481474. Licensed CC0.

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