# APLAUD Trial (Antibiotics vs PLacebo for Acute Uncomplicated Diverticulitis)

> **NCT07492134** · PHASE2 · NOT_YET_RECRUITING · sponsor: **Vanderbilt University Medical Center** · enrollment: 100 (estimated)

## Conditions studied

- Acute Uncomplicated Diverticulitis

## Interventions

- **DRUG:** Amoxicillin-Clavulanate 875 Mg-125 Mg Oral Tablet
- **DRUG:** Placebo
- **DRUG:** Metronidazole
- **DRUG:** Cefuroxime

## Key facts

- **NCT ID:** NCT07492134
- **Lead sponsor:** Vanderbilt University Medical Center
- **Sponsor class:** OTHER
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** NOT_YET_RECRUITING
- **Start date:** 2026-04-01
- **Primary completion:** 2028-04-01
- **Final completion:** 2028-10-01
- **Target enrollment:** 100 (ESTIMATED)
- **Last updated:** 2026-04-21

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07492134

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07492134, "APLAUD Trial (Antibiotics vs PLacebo for Acute Uncomplicated Diverticulitis)". Retrieved via AI Analytics 2026-06-03 from https://api.ai-analytics.org/clinical/NCT07492134. Licensed CC0.

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