# Intracalvariosseous Plus Intravenous Antibiotics for Moderate-to-Severe Bacterial Meningitis

> **NCT07495150** · NA · NOT_YET_RECRUITING · sponsor: **yilong Wang** · enrollment: 86 (estimated)

## Conditions studied

- Blood-Brain Barrier
- Bacterial Meningitis

## Interventions

- **PROCEDURE:** Intracalvariosseous injection vancomycin/tigecycline/polymyxin B
- **DRUG:** Intravenous injection vancomycin/tigecycline/polymyxin B
- **OTHER:** Conventional treatment

## Key facts

- **NCT ID:** NCT07495150
- **Lead sponsor:** yilong Wang
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** NOT_YET_RECRUITING
- **Start date:** 2026-04-01
- **Primary completion:** 2027-04-01
- **Final completion:** 2027-07-01
- **Target enrollment:** 86 (ESTIMATED)
- **Last updated:** 2026-03-27


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07495150

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07495150, "Intracalvariosseous Plus Intravenous Antibiotics for Moderate-to-Severe Bacterial Meningitis". Retrieved via AI Analytics 2026-06-02 from https://api.ai-analytics.org/clinical/NCT07495150. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*