# LasaiON is an Evidence-informed, Multimodal Self-regulation Program Designed to Reduce Emotional Distress and Strengthen Stress-regulation Skills by Combining Transcutaneous Auricular Vagus Nerve Stimulation (taVNS) With Breathing Supported by Heart-rate Variability Biofeedback (HRV-B; emWave).

> **NCT07498881** · NA · NOT_YET_RECRUITING · sponsor: **University of the Basque Country (UPV/EHU)** · enrollment: 200 (estimated)

## Conditions studied

- Adult

## Interventions

- **COMBINATION_PRODUCT:** LasaiON

## Key facts

- **NCT ID:** NCT07498881
- **Lead sponsor:** University of the Basque Country (UPV/EHU)
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** NOT_YET_RECRUITING
- **Start date:** 2026-03-30
- **Primary completion:** 2026-09-03
- **Final completion:** 2028-03-30
- **Target enrollment:** 200 (ESTIMATED)
- **Last updated:** 2026-03-27

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07498881

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07498881, "LasaiON is an Evidence-informed, Multimodal Self-regulation Program Designed to Reduce Emotional Distress and Strengthen Stress-regulation Skills by Combining Transcutaneous Auricular Vagus Nerve Stimulation (taVNS) With Breathing Supported by Heart-rate Variability Biofeedback (HRV-B; emWave).". Retrieved via AI Analytics 2026-06-05 from https://api.ai-analytics.org/clinical/NCT07498881. Licensed CC0.

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