# Psilocybin Assisted Psychotherapy for Treatment Resistant Depression and Co-occurring Substance Use Disorder

> **NCT07499583** · PHASE1,PHASE2 · NOT_YET_RECRUITING · sponsor: **Indiana University** · enrollment: 50 (estimated)

## Conditions studied

- Treatment Resistant Depression
- Substance Use Disorders

## Interventions

- **DRUG:** Psilocybin

## Key facts

- **NCT ID:** NCT07499583
- **Lead sponsor:** Indiana University
- **Sponsor class:** OTHER
- **Phase:** PHASE1,PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** NOT_YET_RECRUITING
- **Start date:** 2026-08-01
- **Primary completion:** 2031-01-01
- **Final completion:** 2031-02-28
- **Target enrollment:** 50 (ESTIMATED)
- **Last updated:** 2026-03-30


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07499583

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07499583, "Psilocybin Assisted Psychotherapy for Treatment Resistant Depression and Co-occurring Substance Use Disorder". Retrieved via AI Analytics 2026-05-31 from https://api.ai-analytics.org/clinical/NCT07499583. Licensed CC0.

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