# Comparative Evaluation of Intraligamentary Injection of Dexamethasone, Diclofenac Sodium, and Chymotrypsin for Enhancing the Success of 4% Articaine Buccal Infiltration in Mandibular Molars With Symptomatic Irreversible Pulpitis

> **NCT07506265** · PHASE4 · COMPLETED · sponsor: **Fayoum University** · enrollment: 105 (actual)

## Conditions studied

- Irreversible Pulpitis (Toothache)

## Interventions

- **DRUG:** Dexamathsone 4mg/ml associated with experimental arm
- **DRUG:** Diclofenac Sodium (DCS)
- **DRUG:** chymotrypsin

## Key facts

- **NCT ID:** NCT07506265
- **Lead sponsor:** Fayoum University
- **Sponsor class:** OTHER
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2025-05-23
- **Primary completion:** 2025-12-29
- **Final completion:** 2026-01-01
- **Target enrollment:** 105 (ACTUAL)
- **Last updated:** 2026-04-06


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07506265

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07506265, "Comparative Evaluation of Intraligamentary Injection of Dexamethasone, Diclofenac Sodium, and Chymotrypsin for Enhancing the Success of 4% Articaine Buccal Infiltration in Mandibular Molars With Symptomatic Irreversible Pulpitis". Retrieved via AI Analytics 2026-05-28 from https://api.ai-analytics.org/clinical/NCT07506265. Licensed CC0.

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