# AMAZE 6: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Knee Osteoarthritis Lose Weight and Reduce Pain

> **NCT07509307** · PHASE3 · RECRUITING · sponsor: **Novo Nordisk A/S** · enrollment: 400 (estimated)

## Conditions studied

- Obesity
- Overweight
- Osteoarthritis, Knee

## Interventions

- **DRUG:** NNC0487-0111
- **DRUG:** Placebo (matched to NNC0487-0111)

## Key facts

- **NCT ID:** NCT07509307
- **Lead sponsor:** Novo Nordisk A/S
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2026-04-20
- **Primary completion:** 2028-08-14
- **Final completion:** 2028-08-14
- **Target enrollment:** 400 (ESTIMATED)
- **Last updated:** 2026-05-15


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07509307

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07509307, "AMAZE 6: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Knee Osteoarthritis Lose Weight and Reduce Pain". Retrieved via AI Analytics 2026-07-02 from https://api.ai-analytics.org/clinical/NCT07509307. Licensed CC0.

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